Buy Recombinant Proteins Extra Quality
Recombinant proteins are produced in the laboratory by cells engineered to express the desired protein. Compared to proteins isolated from natural sources, recombinant proteins offer batch-to-batch consistency, ample supply, and the ability to be optimized for desirable properties (e.g., solubility, stability, potency). The availability of recombinant proteins has accelerated breakthroughs in the understanding protein structure and function, cellular pathways, and many other areas of life science research and therapeutic development.
buy recombinant proteins
Whether conducting basic research or developing next-generation engineered cell therapies, you need to be able to rely on the quality and integrity of the recombinant proteins used in your experiments. As a premiere recombinant protein supplier and manufacturer, Thermo Fisher Scientific offers a large section of high-quality Invitrogen and Gibco brand proteins, including Gibco PeproTech proteins to meet these needs.
RUO All research-grade recombinant proteins are produced in cell culture (mammalian, bacterial, yeast, insect). Every batch is tested for identity, purity, and biological activity using appropriate assays. PeproTech and other Gibco recombinant proteins are designed and tested for cell culture modulation whereas Invitrogen proteins are ideal for use in biochemical and cell analysis applications.
Animal-free Animal-free recombinant proteins are manufactured using only chemically defined, animal-origin free (AOF) materials. Animal-free recombinant proteins are ideal for use in animal studies as well as 3D cell culture models, as they mitigate the risk of spurious results from unknown etiological agents that may exist in animal-derived proteins.
GMP GMP-manufactured recombinant proteins are produced in E. coli to the highest standards with documentation to support ISO and relevant GMP compliance. Extensive quality control tests are performed to help ensure that Gibco PeproGMP recombinant proteins meet the demanding standards for purity, identity, safety, activity, and consistency required for use as ancillary materials in clinical manufacturing.
Gibco Wnt Surrogate-Fc Fusion Protein has been engineered for increased solubility and potency, while activating similar Wnt signaling pathways as most recombinant Wnt3a proteins or Wnt-conditioned media.
Gibco heat-stable recombinant growth factors have been engineered for greater stability in cell culture conditions. Get exceptional performance and retain bioactivity without artificially high concentrations.
For those who seek a consistent supply of recombinant cytokines throughout the drug discovery and development journey, PeproTech cytokines and growth factors are manufactured solely in-house to maintain quality and help provide high compatibility across the RUO-to-GMP spectrum.
Growth factors and cytokines play important roles in cell proliferation and development. Using pure, high quality recombinant growth factors verified to work with Gibco media can help achieve consistently reliable results in cell culture and assay models.
As one of the largest recombinant protein suppliers, Thermo Fisher Scientific offers an extensive catalog of Invitrogen and Gibco brand recombinant proteins, including those sold under the PeproTech name.
View our proteins and enzymes for researching SARS-CoV-2 and other coronaviruses. Our growing list includes spike proteins, papain-like proteases, 3CL proteases and the SARS-Cov-2 nucleocapsid protein. If bulk quantities or proteins prepared in a plate will help with your research, we are happy to explore options and we welcome your request for a quote!
With over 30 years of experience developing and manufacturing recombinant proteins for cytokine and growth factor research, our stringent purification and production standards ensure that our proteins display the highest levels of bioactivity and purity, low endotoxin levels, and lot-to-lot consistency.
For researchers who need defined culture conditions, for those whose preclinical work has the potential of progressing to clinical trials, or for those concerned with animal components due to ethical or regulatory issues, we offer Animal-Free RUO proteins. Our Animal-Free RUO proteins are produced using identical expression systems and manufacturing methods as our Animal-Free GMP-Grade proteins.
Take advantage of our wide range of bioactive recombinant immune checkpoint proteins. From common targets like PD-L1 and CTLA-4 to emerging targets such as butyrophilins and LILRB receptors, we offer a variety of tags and species for studying immune checkpoints.
Explore our expanding catalog of Avi-tag and amine-labeled biotinylated proteins. Our rigorous quality standards ensure that all of our biotinylated proteins display the same level of bioactivity as their unlabeled counterparts and exhibit minimal lot-to-lot variability, so they provide you with the performance and the consistency that you need to optimize your assay.
Utilize our wide selection of fluorescent-labeled recombinant proteins to evaluate the expression of specific chimeric antigen receptors (CARs) on CAR-T or CAR-NK cells, detect cells expressing specific immune checkpoint receptors, or assess SARS-CoV-2 sensitive ACE-2+ cells or immune responses. Fluorescent-labeled proteins allow target cells to be directly stained and detected by flow cytometry.
Only a fraction of the recombinant proteins we make end up as products. We have amassed a huge library of non-catalog proteins that are in stock and available to the customer. Learn more about our available proteins.
Ensure a seamless transition from preclinical research into clinical manufacturing by starting your preclinical experiments with our Animal-Free RUO proteins. R&D Systems Animal-Free RUO proteins are produced in dedicated animal-free laboratories and are manufactured using the same systems as our Animal-Free GMP-Grade proteins.
One of the current challenges in the field of CAR-T cell therapy is the lack of a simple assay to easily detect and quantify CAR expression following T cell transduction. Read this application note to learn about the advantages of using R&D SystemsTM Fluorokines fluorescent-labeled proteins to directly stain and detect CAR+ cells by flow cytometry.
Immune checkpoint proteins play a central role in regulating the activities of different immune cell types and represent some of the most promising targets for cancer immunotherapy. This eBook highlights some of the immune checkpoint molecules that are being investigated as immuno-oncology targets, and the products that we offer for studying these molecules.
Recombinant proteins are a foundational tool for life science research. It used to be common to express proteins in-house, but most researchers can now buy high-quality recombinant proteins that support their research for a fraction of the cost and with fast turnaround.
Aviva Systems Biology has been providing high-quality protein products to the scientific community for over 10 years. In addition to our diverse catalog and semi-custom recombinant protein products, we also offer comprehensive custom recombinant protein expression and production services to meet a variety of research needs.
Over the last few years microalgae have gained increasing interest as a natural source of valuable compounds and as bioreactors for recombinant protein production. Natural high-value compounds including pigments, long-chain polyunsaturated fatty acids, and polysaccharides, which have a wide range of applications in the food, feed, cosmetics, and pharmaceutical industries, are currently produced with nontransgenic microalgae. However, transgenic microalgae can be used as bioreactors for the production of therapeutic and industrially relevant recombinant proteins. This technology shows great promise to simplify the production process and significantly decrease the production costs. To date, a variety of recombinant proteins have been produced experimentally from the nuclear or chloroplast genome of transgenic Chlamydomonas reinhardtii. These include monoclonal antibodies, vaccines, hormones, pharmaceutical proteins, and others. In this review, we outline recent progress in the production of recombinant proteins with transgenic microalgae as bioreactors, methods for genetic transformation of microalgae, and strategies for highly efficient expression of heterologous genes. In particular, we highlight the importance of maximizing the value of transgenic microalgae through producing recombinant proteins together with recovery of natural high-value compounds. Finally, we outline some important issues that need to be addressed before commercial-scale production of high-value recombinant proteins and compounds from transgenic microalgae can be realized.
We provide stable, bioactive human, mouse, and rat recombinant proteins including cytokines, growth factors, and chemokines. Each of our in-house manufactured proteins undergoes rigorous quality testing and has been verified to function in a relevant bioassay. The majority of our recombinant proteins are provided in a convenient, ready-to-use liquid format with a comparable shelf-life to lyophilized proteins.
Our expanding catalog of recombinant proteins includes cytokines, chemokines, growth factors, enzymes, adhesions molecules, and more. These proteins are tested in a variety of bioassays to ensure bioactivity. For studies that are particularly sensitive to contamination with mammalian pathogens, we also offer animal-free versions of many of our recombinant proteins. Like our carrier-free formats, these proteins do not contain any carrier proteins; however, the animal-free products are produced in animal-free media with equipment that is free of all animal components. Browse our recombinant proteins groups below!
Prior to performing bioassay validation and stability testing, we test each recombinant protein for product purity and quantification. In the table below you can find examples of the attributes tested, the test performed, and some acceptance criteria used to ensure that our customers are confident they are receiving the highest quality reagents. 041b061a72